Results for search "Genetics".
Health News Results - 169
Medieval plague outbreaks in England picked up frightening speed in the 17th century, Canadian researchers report.
Their analysis of historical documents covering 300 years showed that outbreaks of the plague doubled every 11 days in London during the 1600s, compared to every 43 days in the 14th century.
"It is an astounding difference in how fast plague epidemics grew," sai...
- Cara Roberts Murez
- October 19, 2020
- Full Page
After starting a drug that's officially approved to treat a type of blood cancer, a young man with type 1 diabetes was able to stop using insulin.
He's been off insulin since August 2018 -- more than two years.
Dr. Lisa Forbes -- his doctor and co-author of a letter describing his case in the Oct. 8 issue of the New England Journal of Medicine -- stopped short of cal...
Genetic problems cause about 14% of cerebral palsy cases, and many of the implicated genes control the wiring of brain circuits during early fetal development, new research shows.
The largest genetic study of cerebral palsy supports previous findings and provides "the strongest evidence to date that a significant portion of cerebral palsy cases can be linked to rare genetic mutati...
Families bond over lots of shared experiences -- but one Leslie Seigel and her adult son, Josh, never expected to share was battling cancer.
Soon after Leslie finished chemotherapy for an aggressive form of breast cancer, however, Josh found himself waging his own battle with testicular cancer.
The mother and son soon learned they shared something else -- a genetic mutation ...
- Serena Gordon
- September 17, 2020
- Full Page
A genetic variant in some people may be associated with mental decline that can't be explained by deposits of two proteins linked with Alzheimer's disease, researchers say.
They said their findings could lead to new treatments for Alzheimer's.
The two proteins are amyloid β and tau. Amyloid forms into plaques and tau forms into tangles. Both are found in the brains of A...
- Robert Preidt
- September 16, 2020
- Full Page
Researchers say your biological sex affects gene expression in nearly every type of tissue -- influencing body fat, cancer and birth weight.
Gene expression is the amount of product created by a gene for cell function, the international team of researchers explained.
They said their findings could prove important for personalized medicine, creating new drugs and predicting p...
- Robert Preidt
- September 15, 2020
- Full Page
Asthma treatments tailored to the genes of kids and teens could help improve control of their symptoms, new research suggests.
The study included 241 adolescents, aged 12 to 18, who were randomly selected to receive either traditional asthma treatment or "personalized medicine" -- treatment based on their individual genetics.
During a year of follow-up, those in the personal...
- Robert Preidt
- September 8, 2020
- Full Page
Disturbed sleep doesn't cause Alzheimer's disease, but some sleep patterns may be more common in people who have a high genetic risk for it, a new study reports.
Those patterns include being a morning person, having shorter sleep duration and being less likely to have insomnia, according to findings published in the Aug. 19 online issue of the journal Neurology.
Scientists have discovered that the types of fungi living in the lungs play a big part in severity of a life-threatening condition called acute respiratory distress syndrome (ARDS).
In ARDS -- a condition developed by many patients with severe cases of COVID-19 -- the lungs are unable to supply adequate oxygen to vital organs. Patients with ARDS are usually placed on ventilators.
- Steven Reinberg
- August 24, 2020
- Full Page
It may be possible to protect Parkinson's patients' brains from further damage by turning off a "master regulator" gene, researchers report.
"One of the biggest challenges in treating Parkinson's, other than the lack of therapies that impede disease progression, is that the disease has already laid waste to significant portions of the brain by the time it is diagnosed," said researche...
Stroke is more deadly among Black people than whites, and the reason may come down to genetics.
Researchers who studied the genomes of more than 21,000 Black people found that a common variation near the HNF1A gene was tied to an increased risk of stroke in people of African descent.
The gene has been linked to stroke and heart disease.
"Given the undue burden t...
- Steven Reinberg
- August 13, 2020
- Full Page
Scientists are well on the way to understanding more about how genes can cause stillbirth, new research suggests.
In the study, researchers used genetic analyses to identify gene mutations that are linked to stillbirth, which is the in utero death of a fetus after 20 weeks' gestation. The findings might help doctors counsel parents who have experienced a stillbirth.
- Steven Reinberg
- August 12, 2020
- Full Page
As researchers hone in on ways to detect whether someone has a high risk of developing Alzheimer's disease before they have any symptoms, mental health professionals have worried what the psychological fallout of that knowledge might be.
But new research suggests that people can handle the truth.
In the study, seniors who didn't have any Alzheimer's symptoms underwent a sp...
Among people who have the gene that carries a heightened risk for early-onset Alzheimer's disease, a new study suggests that more education might slow the development of beta-amyloid plaques in the brain.
About 1% to 6% of people with Alzheimer's disease have genes that put them at risk for early development of the disease, which can start in their 30s to 50s, the researcher...
The Vikings had smallpox and may have spread it wherever they ventured, scientists report.
That conclusion stems from an examination of teeth from 1,400-year-old Viking skeletons that contained extinct strains of smallpox. The genetic structure of those strains differed from that of the modern smallpox virus eradicated in the 20th century, the researchers found.
Some people in their 90s stay sharp whether their brain harbors amyloid protein plaques -- a hallmark of Alzheimer's disease -- or not, but why?
That's the question researchers sought answers for among 100 people without dementia, average age 92, who were followed for up to 14 years. Their answer? A combination of genetic luck and a healthy, fulfilling lifestyle.
"The vast ...
Scientists who have identified the early smallpox strains used to create vaccines against the disease say this type of genetic research could help efforts to develop a vaccine against the new coronavirus.
Smallpox was among the most dangerous viral diseases in human history, killing about three of every 10 people who were infected. Many of those who survived were disabled, blind or di...
Dutch researchers have identified a common genetic variant as a cause of deafness, and say it could be a good target for gene therapy.
Deafness in adults is known to be inherited but, unlike childhood deafness, the genetic causes aren't clear.
To date, 118 genes have been linked to deafness. Variants in these genes explain much of the deafness present at birth and in childho...
Although much of the genetic makeup of humans has been mapped, hundreds of missing DNA sequences remain.
Scientists from the U.S. National Human Genome Research Institute report they have produced the complete DNA sequence of a single human chromosome. That discovery could allow researchers to sequence the entire human genome.
"This accomplishment begins...
The progression of Alzheimer's disease may accelerate as iron deposits build up in the brain, a new study finds, hinting at a possible role for the mineral in mental decline.
Using MRI scans of 200 older adults with and without Alzheimer's, researchers found that those with the disease generally had higher iron levels in various parts of the brain. And 17 months later, Alzheimer's pat...
Your genes may have a big impact on bacteria in your wounds and how quickly you heal, new research shows.
The researchers said their findings could help improve wound treatment.
Chronic wounds -- ones that don't show signs of healing within three weeks -- can be costly, and bacterial infection slows the process.
A range of bacterial species are present in chronic w...
Very sensitive people may owe about half of their heightened feelings to their genes, a British study of twins suggests.
Researchers looked at pairs of identical and fraternal 17-year-old twins to gauge how much differences in sensitivity owed to genes or the environment.
While identical twins share the same genes, fraternal twins don't, so findings among identical twins a...
Screening for breast and ovarian cancer genes might be added to the list of medical tests that can be safely and effectively done from home, new research suggests.
The study looked at screening for BRCA1, BRCA2 and other gene mutations linked to an increased risk of breast and ovarian cancer. Women with a BRCA1 or BRCA2 mutation have as much as a 7 in 10 chance of getting breast canc...
Very few people with autism receive two recommended genetic tests, a new study finds.
The American Academy of Pediatrics and other medical groups recommend offering chromosomal microarray testing and Fragile X testing to people with autism, to detect or rule out genetic abnormalities that could affect their diagnosis and care.
For the study, the researchers analyzed data gat...
A child with an uncle or aunt with autism appears to have a more than doubled risk of being diagnosed with an autism spectrum disorder themselves, a new U.S. government-funded study reports.
Roughly 3% to 5% of children with an aunt or uncle with autism can also be expected to have some form of autism, compared with just 1.5% of children overall, according to the study fun...
It was already known that genetics can play a role in drinking problems, but now researchers have identified additional gene variants that could help identify many more at-risk people.
The team conducted a genome-wide analysis of more than 435,000 people of European ancestry to look for shared gene variants among people with problem drinking.
The researchers pinpointed 19 ne...
People who have a flawed gene linked to Alzheimer's disease may face a higher risk of COVID-19, an international team of researchers reports.
Part of the increased risk among people with dementia may owe to high rates of new coronavirus infections in nursing homes. But this study suggests genetics may also be a factor.
The APOE e4e4 gene variant is known to increase Alzheime...
Black and white women share genes that increase the risk for breast cancer, a new study finds.
These genes include BRCA1, BRCA2 and PALB2, each of which is associated with a more than sevenfold risk of breast cancer. Women of both races also share four other genes linked with a moderately increased risk, according to researchers.
"This means that the multi-gene panels that...
They're small spiny mammals that look like anteaters with scales.
And pangolins -- which some credit with playing a role in the emergence of the new coronavirus -- might hold clues to fighting COVID-19.
Genetic research into the new coronavirus has suggested that it originated in bats, found its way into pangolins sold at Chinese "wet markets," and then migrated into humans....
A new study suggesting that the new coronavirus has mutated to become even more infectious should be viewed with skepticism, multiple experts said Wednesday.
Earlier this week, researchers at Los Alamos National Laboratory concluded that the new strain of the coronavirus started spreading in Europe in early February and then expanded to other parts of the world, becoming the dominant ...
A new, mutated strain of the coronavirus that causes COVID-19 has become dominant and appears to be more contagious than the strain that spread during the early stages of the pandemic, scientists report.
They said the new strain appeared in February in Europe, spread to the East Coast of the United States and has been the dominant strain worldwide since mid-March, the Los Angeles ...
Lots of boozing might increase your risk for a stroke, Swedish researchers report.
Heavy alcohol use can triple your risk for peripheral artery disease, a narrowing of arteries that results in reduced blood flow, usually to the legs. It can also increase your risk for stroke by 27%. There's also evidence of a link to coronary artery disease, atrial fibrillation and aortic aneurys...
Herpes simplex virus -- the virus that causes cold sores -- is more complex than scientists had thought, a new study finds.
It had been believed that there were about 80 so-called open reading frames in the herpes gene, but there now appear to be 284, researchers report. Those are places where the DNA becomes proteins.
"The new findings now make it possible to study the in...
A new oral polio vaccine promises to help make polio a disease of the past, according to the results of a phase 1 clinical trial.
Polio was almost eliminated worldwide -- except in vaccine-induced cases. In those cases, the weakened virus used in vaccines developed the ability to escape from immunized individuals and spread in places with low vaccination rates.
The new des...
Researchers say they've developed a low-cost swab test that can diagnose COVID-19 infections in about 45 minutes.
The CRISPR-based test -- which uses gene-targeting technology and requires no specialized equipment -- could help relieve testing backlogs in the United States as COVID-19 continues to spread, the scientists said.
The U.S. Food and Drug Administration has not app...
Whether you have a low or a high genetic risk for type 2 diabetes, obesity seems to be the driving factor in developing the disease, Danish researchers say.
Their new study found that obesity increased the risk of type 2 diabetes by at least six times, no matter what a person's genetic risk was.
"Obesity and unfavorable lifestyle are associated with increased risk of type ...
People who carry a gene called APOE4 face an increased risk of Alzheimer's. But that effect may be lessened if they got luckier with a different gene, researchers have found.
Scientists have long known that the APOE gene is the strongest genetic influence over whether people develop Alzheimer's late in life. Those who carry a form of the gene called E4 have a higher-than-average risk....
Genetic mutations that put some younger people at high risk for severe illness from the new coronavirus will be investigated in an international study.
Plans call for enrolling 500 patients worldwide who are under age 50, have been diagnosed with COVID-19 and admitted to an intensive care unit, and have no underlying health problems such as diabetes, heart disease or lung disease.
Despite internet rumors to the contrary, the new coronavirus arose from natural causes and was not concocted in a lab, according to scientists who conducted a detailed genomic examination of the virus.
SARS-CoV-2, the virus that causes COVID-19 illness, shows zero evidence of being artificially engineered, reported a team who published their findings March 17 in Nature Medicine...
A test that can detect the genetic "fingerprint" of prostate cancer in blood could improve diagnosis, monitoring and treatment of the disease, researchers say.
The test checks for prostate cancer DNA in blood in order to provide the earliest evidence that prostate cancer is active.
This could help doctors monitor tumor behavior, determine if cancer has spread ("metastasized"...
The exact method that's now cured two men of HIV infection is not one that's going to be widely available to the nearly 38 million people worldwide living with the virus, experts say.
Still, the news has rekindled hopes of finally winning the war against the virus that causes AIDS.
The Berlin and London patients benefited from a combination of medical and genetic chance, the...
A significant number of older women with breast cancer may have genetic mutations that put them at risk of additional cancers, particularly ovarian cancer, a new study finds.
The researchers said that as many as one in 40 postmenopausal women with breast cancer before age 65 has a mutation in the BRCA1 or BRCA2 genes.
Currently, the guidelines emphasize genetic testing in ...
Experts have long known about a quirky postscript to stressful events like earthquakes and terrorist attacks: The ratio of boys and girls born temporarily turns upside down.
Now, Canadian researchers are reporting the same change in Ontario's birthrates following Republican Donald Trump's victory in the 2016 U.S. presidential election.
The percentage of boys born in Canada's...
People who vape have potentially cancer-causing changes in their DNA similar to those found in cigarette smokers, according to a new study.
These chemical alterations -- called epigenetic changes -- can cause genes to malfunction. They are found in nearly all types of cancer, as well as other serious diseases, the researchers noted.
"That doesn't mean that these people are g...
- Robert Preidt
- February 17, 2020
- Full Page
A genetic variant associated with Alzheimer's disease increases the risk of dementia in people with Parkinson's disease, researchers say.
The finding could lead to new treatments for dementia in Parkinson's patients, according to the team at Washington University School of Medicine in St. Louis.
Parkinson's disease is a progressive neurological disorder that causes tremors, ...
In a first, scientists have used gene-editing technology to create "designer" immune system cells that can fight tumors and survive for months in cancer patients' bodies.
It's a proof of principle, the researchers say -- and an early step toward bringing the gene-editing tool known as CRISPR into cancer treatment.
CRISPR allows researchers to precisely "snip" bits of DNA wit...
A rare, inherited muscle disorder that occurs in about 1 in 8,000 people, myotonic dystrophy also can affect the heart and other organs. A new set of expert recommendations offers guidance for managing the progressive condition.
"Your average cardiologist doesn't see this all the time, so it can often get overlooked," said lead author, Dr. Elizabeth McNally. "We want to make sure peo...
A breakthrough study has identified a class of natural gene variants that may protect against Alzheimer's disease.
For the study, researchers at University College London analyzed DNA from more than 10,000 people -- half with Alzheimer's and half without. The investigators found that these gene variants reduce the functioning of proteins called tyrosine phosphatases.
Cancer is a genetically driven disease, and a mother lode of new genetic data on dozens of different cancers is promising to break open fresh avenues of prevention and treatment.
Nineteen out of 20 cancers now can be tracked back to one or more specific genetic mutations, based on data gathered from in-depth sequencing of thousands of whole-cancer genomes, researchers say.
- Dennis Thompson
- February 5, 2020
- Full Page
As China races to stem the spread of a new coronavirus that has now infected nearly 10,000 people and killed more than 200, researchers report that a novel approach to gene sequencing could help monitor coronaviruses more effectively.
Coronaviruses in bats have been linked to the outbreak from the virus labeled 2019-nCoV, as well as outbreaks of diseases like SARS and MERS.