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Hydroxychloroquine, the malaria drug touted and reportedly used by President Donald Trump as a preventative for COVID-19, appears not to have lived up to its hype, a new study shows.

Unlike some prior studies, this new trial was a "gold standard" prospective, randomized clinical trial. It found that hydroxychloroquine could not prevent COVID-19 any better than a sugar pill.

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Taking benzodiazepines -- drugs such as Xanax, Valium, Klonopin, Halcion or Ativan -- to treat anxiety or insomnia before pregnancy boosts the risk of an ectopic pregnancy, new research suggests.

Ectopic pregnancy is a pregnancy that develops outside the uterus, typically in a fallopian tube. The risk of ectopic pregnancy was nearly 50% higher for women who had filled a prescript...

A drug championed by President Donald Trump as a coronavirus panacea appears to be in short supply for people who really need it: lupus patients.

More than one-third of U.S. lupus patients who take hydroxychloroquine have struggled to fill prescriptions for the drug during the COVID-19 crisis, a new survey finds.

One patient finally filled her prescription after three weeks ...

As the evidence piles up that a malaria drug touted as a possible coronavirus treatment by President Donald Trump may instead harm patients, a new study shows the same might hold true for cancer patients with COVID-19.

Researchers found that cancer patients with COVID-19 who receive both hydroxychloroquine and the antibiotic azithromycin have a higher risk of death than those who aren...

Many patients with heart failure might live years longer if they were on a combination of newer medications, a study suggests.

Researchers estimate that if certain heart failure patients were prescribed a four-pill regimen -- including three recently proven therapies -- they could live up to six years longer, compared with the regimen patients commonly use.

The findings, pub...

Boosting doses of opioid pain medicines doesn't appear to benefit patients with chronic pain, researchers report.

"What we found was that the pain relief the provider and the patient are going for really isn't there when they increase their doses," said study author Corey Hayes, an assistant professor at the University of Arkansas College of Medicine.

"You don't see the ben...

In the race to find treatments for COVID-19, the antiviral drug remdesivir has gotten much of the attention. But researchers say a class of long-used drugs called interferons also looks promising.

Trials testing the medications are underway in several countries. A small study published last week in The Lancet found that a three-drug regimen, containing an interferon, helped hos...

Sense of smell most often diminishes by the third day of infection with the new coronavirus, and many patients also lose their sense of taste at the same time, a new study finds.

The findings may help identify patients most likely to benefit from antiviral treatment, according to the researchers.

"The relationship between decreased sense of smell and the rest of the COVID-19...

Since the coronavirus pandemic began, rates of hospital admission and death from COVID-19 have been significantly higher in men than women.

Now, new Dutch research suggests a reason why: Compared to women, men have higher concentrations of a blood enzyme that helps the new coronavirus infect human cells.

The enzyme is called angiotensin-converting enzyme 2 (ACE2).

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Daily use of inhaler medication by Americans with asthma and chronic obstructive pulmonary disease (COPD) has increased during the coronavirus pandemic, a new study shows.

Researchers analyzed data on controller inhaler use by nearly 7,600 patients who use Propeller Health, which uses electronic medication monitors to track inhaler use and alerts patients about missed doses.

Another study casts doubt on the malaria drugs touted by President Donald Trump as potential game-changers against COVID-19.

The drugs, chloroquine and hydroxychloroquine, are also used for lupus and rheumatoid arthritis. But Trump and others have promoted their use as treatments for the coronavirus that has sickened millions around the world.

Now, a research review in the...

When the President of the United States offers medical advice, many Americans will heed the call. Never mind that the recommendations may be unfounded and potentially dangerous.

That's the cautionary finding of an analysis published April 29 in JAMA Internal Medicine.

Researchers examined Google search patterns following President Donald Trump's public embrace of the...

Cardiac rehabilitation programs improve heart attack survivors' quality of life, especially if they get lots of exercise, a new British study finds.

A heart attack can reduce quality of life due to struggles with mobility and self-care, as well as daily leisure and work activities.

Many heart attack survivors take part in cardiac rehab, which emphasizes exercise, quitting sm...

Hydroxychloroquine is a key therapy for the autoimmune disease lupus, but interest in it as a potential COVID-19 treatment could make it hard for lupus patients to obtain, experts warn.

Hydroxychloroquine is the only medication known to increase survival in patients with systemic lupus. That's the most common form of lupus, a disease in which the immune system attacks different parts ...

Dozens of drugs are being investigated for their value in treating COVID-19, as desperation drives doctors and researchers to look for something that could battle the virus and save lives.

"There are really no FDA-approved medications for the treatment of COVID-19, unfortunately," said Ashley Barlow, a pharmacy resident with the University of Maryland Medical Center in Baltimore. "We'...

As researchers hunt for ways to treat severe COVID-19 infections, a new trial will ask whether an old arthritis drug can prevent serious complications in the first place.

The medication, called colchicine, is an oral anti-inflammatory that has long been prescribed for gout, a form of arthritis. Its history goes back thousands of years, and the drug was first sourced from the autumn cr...

There's a lot of confusion about medications and COVID-19, so experts offer some answers.

There are no proven drug treatments for the illness caused by the new coronavirus, so doctors sometimes use drugs approved for other conditions to treat seriously ill COVID-19 patients. This is called off-label use.

One drug being investigated as a possible COVID-19 treatment is hydroxy...

Despite increased demand for inhalers in some parts of the United States, Americans with asthma shouldn't ration their medications during the coronavirus pandemic, the American Lung Association says.

Rescue inhalers are in short supply in some areas because hospitals are giving albuterol to COVID-19 patients with severe symptoms to help them breathe, the group explained. Albuterol is ...

An experimental drug may ease a range of symptoms that strike people with schizophrenia, without the side effects of existing medications, an early clinical trial suggests.

Researchers found that, over one month, the drug helped manage the different ways in which schizophrenia manifests -- from delusions and hallucinations, to flattened emotions and social withdrawal.

Among ...

Nine-month-old Maisie Gillan spent just a few moments crawling around on a neighbor's floor, near the end of a dinner party meant to welcome her family to the community.

The next morning her parents woke to discover Maisie cold and lifeless. Paramedics responded quickly but couldn't revive the baby.

Police later figured out Maisie had accidentally ingested methadone that a r...

People with high blood pressure and heart disease may be vulnerable to complications from COVID-19, heart experts say.

Nearly half of Americans have high blood pressure, according to the American Heart Association (AHA).

Based on current knowledge, seniors "with coronary heart disease or high blood pressure may be more susceptible to the coronavirus and more likely to devel...

As hospitals give more and more COVID-19 patients albuterol to help them breathe, people with asthma may have a hard time getting an inhaler.

The American College of Allergy, Asthma and Immunology (ACAAI) said some areas of the United States are experiencing shortages of albuterol inhalers, and the shortage may spread.

But Dr. Michael Blaiss, exe...

Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions, the U.S. Food and Drug Administration warns.

Problems may occur in EpiPen 0.3 mg and EpiPen Jr 0.15 mg auto-injectors and authorized generic versions due to device malfunctions and user errors, according to the agency.

The devices may...

A new trial confirms that the drug selumetinib shrinks tumors in children suffering from neurofibromatosis type 1.

The condition is characterized by changes in skin coloring and the growth of tumors along nerves in the skin, brain and other parts of the body. The tumors cause disfigurement, limitations on strength and range of motion, and pain.

The tumors are hard to treat,...

Two types of heart medications do not make coronavirus infection worse, three major U.S. medical groups say in a new joint statement meant to dispel misinformation about the use of the medications in people with COVID-19.

The American Heart Association (AHA), the Heart Failure Society of America and the American College of Cardiology (ACC) recommend continuation of angiotensin-...

The advent of HIV-suppressing drugs has ushered in a new era of "pre-exposure prophylaxis" (PrEP) that drastically cuts a sexually active person's odds of contracting the virus.

But wider access to PrEP is being threatened by pharmaceutical company efforts to curb the use of cheap, new generic forms of these medicines, researchers argue in a new study.

The study authors said...

If your doctors keep giving you prescriptions for antibiotics, you might be at increased risk of hospitalization for a serious infection, a new report suggests.

For the study, researchers analyzed data from 2 million patients in England and Wales. These patients had received prescriptions for antibiotics between 2000 and 2016 to treat common infections such as upper respiratory tract,...

An Ebola drug that's proven effective against some coronaviruses may also work against the new COVID-19 coronavirus, scientists say.

Remdesivir was developed by Gilead Sciences in response to the 2014 West African Ebola virus epidemic.

"We know the drug works against different coronaviruses, like MERS [Middle East respiratory syndrome] and SARS [severe acute respiratory syn...

While the world's focus is trained on the new coronavirus, a groundbreaking clinical trial finds researchers battling a tough-to-treat form of an "old" infectious disease, tuberculosis.

TB is a bacterial infection that usually attacks the lungs. The disease does not get much attention in wealthy nations, where it's less common. The United States saw about 9,000 cases in 2018, accordin...

Over the course of a decade, the net cost of prescription drugs in the United States rose more than three times faster than the rate of inflation, a new study finds.

The net cost of a drug refers to the sticker price minus manufacturer discounts.

Researchers in the University of Pittsburgh's Center for Pharmaceutical Policy and Prescribing (CP3) conducted the analysis on net...

Helping older people manage their prescribed medicines after they leave the hospital reduces their risk of readmission, researchers say.

Many older patients take multiple medicines and these often change after a hospital stay. This can cause misunderstandings that result in patients taking too much or too little of their medications, or not taking them at all, the authors of the new s...

People who use marijuana either medicinally or recreationally should remember that pot can have potentially harmful interactions with medications they take regularly, a new report warns.

This is particularly true of older folks, who often are on many different drugs to manage a variety of chronic ailments, said lead researcher Tony Antoniou. He's an associate professor in the departme...

Opioid use in Florida fell after a law that restricted opioid prescriptions for acute pain was introduced in 2018, researchers report.

Under the law, opioid prescriptions for acute pain are limited to a three-day supply (with certain exceptions), and physicians and pharmacists must use the state's prescription drug monitoring database to review a patient's prescription history.

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The first generic version of Daraprim (pyrimethamine) tablets for the treatment of toxoplasmosis has been approved by the U.S. Food and Drug Administration.

"Today's approval is especially important for populations that are more susceptible to toxoplasmosis infections, such as pregnant women and individuals with HIV or AIDS, by paving the way for more choices in treatment options," FD...

A new monitoring approach could help improve treatment of patients with tuberculosis (TB), researchers say.

TB is an infectious disease that primarily affects the lungs. Treatment involves multiple pills or injection drugs daily for at least six months. Successful treatment depends on the medications reaching pockets of TB bacteria in the lungs.

Researchers have developed a ...

The immunotherapy drug Keytruda might offer a new treatment option to women with an aggressive form of breast cancer, a clinical trial suggests.

The study found that for women with "triple-negative" breast cancer, adding Keytruda to standard chemotherapy improved their odds of responding.

And in the months afterward, women treated with the drug were less likely to see their ...

Taking their medications as prescribed significantly lowers lupus patients' risk of developing diabetes, a new study finds.

Type 2 diabetes is a common complication of lupus, an autoimmune disease that can cause damaging inflammation in many organs, as well as rashes, fatigue and joint pain.

For the new study, researchers analyzed four years of data on nearly 1,500 lupus pat...

American doctors prescribe more brand-name medications after they get a free lunch or other incentives from drug company marketers, a new study finds.

Researchers analyzed drug prescribing between 2013 and 2015 for a large sample of enrollees in Medicare Part D. The federal program, which subsidizes prescriptions for 37 million seniors and disabled people, accounts for nearly one-thir...

Rising drug costs are hampering the care of patients with debilitating neurological disorders like Parkinson's disease and Alzheimer's, a new study finds.

Patients are less likely to fill necessary prescriptions as out-of-pocket costs increase, said senior researcher Dr. Brian Callaghan, a neurologist with the University of Michigan, in Ann Arbor.

"It's a pretty predictable ...

Many Americans battling autoimmune illnesses such as rheumatoid arthritis or psoriasis turn to a long-used drug, methotrexate, for relief.

But until now there's been little comprehensive research on side effects tied to the drug.

A new study funded by the U.S. National Institutes of Health may fill that gap. It finds that patients who take methotrexate do have a slight-to-mo...

If you are sometimes less than careful with your prescription medications and have young kids at home, a new study shows how easily tragedies can occur.

Researchers found that young children getting into medicines leads to about 400,000 poison center calls and 50,000 emergency department visits in the United States each year.

In more than half of these cases, medications hav...

In the midst of a U.S. epidemic of opioid abuse, knowing how to quickly administer the anti-overdose drug naloxone could save a life.

Now, research finds that delivering naloxone via nasal spray could be the quickest and easiest of three methods of administration.

"Our goal was to see if there was a method that was the most intuitive," said William Eggleston, a clinical ass...

Viagra can salvage a man's sex life, but in rare cases it may temporarily steal his sight.

Researchers report that some men who took sildenafil -- the generic form of the impotence drug -- suffered from vision problems, including a kind of color blindness that could take weeks to resolve.

The case report details 17 Turkish males who wound up in the hospital after taking sil...

Nearly half of antibiotic prescriptions for Medicaid patients appear to be inappropriate, new research suggests.

That kind of overprescribing raises risks for everyone, experts say, as bacteria gain more chances to mutate around the life-saving drugs.

For the study, researchers analyzed 298 million antibiotic prescriptions filled by 53 million Medicaid patients between 2004 ...

Some people let healthy habits fall by the wayside after they start medications for high cholesterol or high blood pressure, a new study finds.

Of more than 41,000 middle-aged Finnish adults researchers followed, those who started on cholesterol or blood pressure drugs were more likely to stop exercising or gain weight in the years afterward.

The pattern does not prove that ...

American dentists often prescribe more than the recommended supply of opioid painkillers to patients, a new study finds.

Not only that, they are more likely to prescribe more powerful opioids, the researchers found.

In this study, the researchers analyzed data on nearly 550,000 dental visits by adult patients between 2011 and 2015, before U.S. Centers for Disease Control and...

The U.S. government aims to end the HIV epidemic by 2030, but skyrocketing medication costs may make that a pipe dream, a new study suggests.

Since 2012, the cost of antiviral treatment for HIV, the virus that causes AIDS, has jumped 34%. That's nearly four times the inflation rate.

Even with new generic options, initial treatments now top $36,000 per patient per year,...

Allowing pharmacists to provide the opioid overdose drug naloxone without a prescription led to a huge increase in dispensing of the lifesaving drug in Ohio.

Ohio state lawmakers gave that permission in 2015. Since then, there's been a 2,328% increase in naloxone dispensing, according to University of Cincinnati researchers.

The study also found that counties with low-em...

When a child has strep throat, an antibiotic like penicillin usually has them back at school 24 hours later.

But a new study warns that strains of bacteria that cause strep throat and "flesh-eating disease" appear close to becoming resistant to penicillin and other antibiotics known as beta-lactams.

"If this germ becomes truly resistant to these antibiotics, it would have a ...

Nearly half of all opioid doses and more than a quarter of all opioid prescriptions in the United States come from 1% of health care providers, a new study says.

The authors said this suggests that efforts to reduce overuse of prescription opioid painkillers should not focus on strict limits for all doctors but on a small percentage.

"Most p...