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Results for search "Alzheimer's".

29 Jul

HealthDay Now: Alzheimer’s Drug Approval Harms FDA’s Reputation

In a HealthDay Now interview, we spoke with Dr. G. Caleb Alexander, a professor at Johns Hopkins. He served on the FDA advisory committee that nearly unanimously advised against approving Biogen's controversial new Alzheimer's drug. Dr. Alexander discusses whether the FDA's reputation will take a permanent hit due to the drug's approval despite limited evidence of benefit.

29 Jun

4 Ways To Reduce Your Alzheimer’s Risk

Following a healthy lifestyle helps protect your brain and lower your risk of dementia

07 May

Eating A Mediterranean Diet Helps Prevent The Loss Of Brain Function, Study Finds

Following a diet rich in fruits, vegetables, fish and olive oil may protect your brain against protein build-up and shrinkage related to Alzheimer's disease, researchers say.

Health News Results - 235

'Mild Cognitive Impairment' in Older Age Often Disappears, Study Finds

A diagnosis of mild cognitive impairment (MCI) might worry an older adult, who could see it as a stepping stone to dementia. But a new study suggests one does not necessarily lead to the other.

In fact, nearly half of seniors tracked in the study -- all of who had been diagnosed with issues in memory and thinking and received an MCI diagnosis -- no longer had the condition a few years lat...

Could Coffee Help Lower Your Odds for Alzheimer's?

Coffee lovers know a steaming cup of java can quickly deliver energy and mental clarity every morning, but new research suggests it may also guard against Alzheimer's disease in the long run.

"Worldwide, a high proportion of adults drink coffee every day, making it one of the most popular beverages consumed," said lead researcher Samantha Gardener, a post-doctoral research fellow at Edith...

Low-Dose Aspirin Won't Affect Dementia Risk in People With Diabetes

Low-dose aspirin neither reduces nor increases the risk of dementia in adults with type 2 diabetes, a new study finds.

"This is reassuring that an increase in the risk of dementia is unlikely for the millions of people worldwide who regularly take aspirin to protect against the risk of heart attack and stroke," according to study author Jane Armitage, of the University of Oxford in Englan...

Neurologists' Group Issues Guidance to Families on Controversial Alzheimer's Drug

Neurologists must make sure Alzheimer's patients and their families understand that the controversial drug aducanumab does not restore mental function, the American Academy of Neurology (AAN) said in new position statement that includes ethical guidelines.

"Aducanumab is not a cure for Alzheimer's disease, yet since it has been approved by the [U.S. Food and Drug Administration], patients...

Reminder Apps on Smartphones May Help in Early Dementia

Despite stereotypes about seniors and technology, a small study suggests that older adults in the early stages of dementia can use smartphone apps as memory aids.

The researchers found that older people with mild impairments in memory and thinking were not only able to learn how to use the apps, they said the digital aids made their daily lives easier.

The apps were not specially de...

Trial Begins of Nasal Vaccine for Alzheimer's Disease

The first human clinical trial of a nasal vaccine to slow the progression of Alzheimer's disease is set to begin after nearly 20 years of research.

This is a "remarkable milestone," according to Dr. Howard Weiner, co-director of the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital in Boston.

"Over the last two decades, we've amassed preclinical evidence sugg...

Pricey Alzheimer's Drug Drives Spike in Medicare B Premium: Officials

A new and expensive Alzheimer's drug called Aduhelm is responsible for about half of the $21.60 increase in monthly premiums for Medicare's Part B outpatient program in 2022, Medicare officials report.

The new premium will be $170.10 a month, and the $21.60 boost is the biggest increase ever in dollar amount, but not in percentage terms. As recently as August, a smaller increase of $10 fr...

Alzheimer's Diagnosis May Come With Big Cost to Social Life

Alzheimer's is a devastating disease, slowly robbing patients of their memories and even their sense of selves.

Now, new research shows it also robs sufferers of a healthy social life.

"Social relationships are an essential feature of our quality of life and can buffer against cognitive decline," said study co-author Addam Reynolds, a doctoral candidate at the Rutgers School of Soci...

Many People May Be Eating Their Way to Dementia

Eating lots of fruits, veggies, beans and other foods with inflammation-cooling properties may lower your odds of developing dementia as you age.

But, if your diet is loaded with pro-inflammatory foods, you may be up to three times more likely to experience memory loss and issues with language, problem-solving and other thinking skills as you age, new research suggests.

"A less infl...

Could Estrogen Help Shield Women's Brains From Alzheimer's?

A key to reduced Alzheimer's disease risk in women could be how much of the hormone estrogen they're able to stockpile over the years, new research suggests.

Certain lifetime choices — such as having more children, taking hormonal birth control or taking hormone therapy during menopause — mean that a woman has greater cumulative exposure to estrogen during her lifetime. A longer ...

Fish on Your Plate May Keep Your Brain Sharp

Older folks who eat fish a couple of times a week may be doing their brains a favor.

New research suggests that fish, even in moderate amounts, helps stave off vascular disease that may ultimately lead to dementia.

"Previous studies, including work from our team in France and others in the U.S., reported protective associations of eating fish against cognitive decline and risk of de...

Purrfect Pal: Robotic Cats May Help People With Dementia

If you have a pet, you know that the excited wag of your dog's tail or the satisfied purr of your cat curling up on your lap can be a mood booster.

But what if that pet is a robot? And what if its owner has dementia?

In a small study, researchers at Florida Atlantic University found that engaging with a robotic pet might help people with Alzheimer's disease or a related dementia, re...

Fitter in 1820: Today's Americans Spend Much Less Time Being Active

Modern Americans get much less physical activity than their forebearers did 200 years ago, and increasing reliance on technology is a major reason why.

That's the finding from researchers who used data on falling body temperature and changing metabolic rates in the United States to measure de...

Could Breastfeeding Help Women Keep Their Smarts as They Age?

Might breastfeeding affect a new mother's future brain health?

That's the intriguing question posed by a new study that flips the narrative from the often-touted benefits for baby to what impact breastfeeding might hold for Mom years later.

Researchers from UCLA Health found that women over age 50 who had breastfed their babies performed better on tests of brain function than those ...

Right Amount of Sleep May Be Important in Early Alzheimer's

Getting the right amount of sleep — not too much and not too little — could reduce your risk of mental decline as you age, even if you have early Alzheimer's disease, a new study claims.

Poor sleep and Alzheimer's disease are both associated with thinking ("cognitive") declines, but separating out the effects of each has been a challenge.

This new study included 100 older adults...

Depression in Early Life May Up Dementia Risk Later

Happy young adults may be somewhat protected from dementia, but the reverse may be true, too: If you're a depressed young adult, your odds for dementia rise, a new study suggests.

"Generally, we found that the greater the depressive symptoms, the lower the cognition and the faster the rates of decline," researcher Wil...

Scientists Untangle Why Diabetes Might Raise Alzheimer's Risk

Type 2 diabetes may up the risk for Alzheimer's disease by altering brain function, new animal research suggests.

A University of Nevada Las Vegas team showed that chronically high blood sugar could impair memory and alter aspects of working memory networks in rodents.

"Diabetes is a major risk factor for developing Alzheimer's disease, but it is not clear why," said study author Ja...

MIND Diet May Guard Against Alzheimer's

WEDNESDAY, Sept. 29, 2021 (HealthDay News) - - The MIND diet may help older people ward off Alzheimer's disease, a new study finds.

Developed by the late Martha Clare Morris, who was a Rush University nutritional epidemiologist, and her colleagues, the MIND diet is a hybrid of the Mediterranean and DASH diets.

People in the study who followed the MIND diet even later in life did not...

Signs of Early Alzheimer's May Be Spotted in Brain Stem

Certain changes in a part of the brain stem, visible in scans, might be a potential early indicator of Alzheimer's disease, a new study suggests.

Using different brain imaging techniques, researchers found that lesser "integrity" in the brain stem region was linked to a faster decline in memory and thinking in older adults, as well as certain brain changes seen in early Alzheimer's.

Common Eye Conditions Tied to Higher Risk for Dementia

Diseases that can rob you of vision as you age also appear to be tied to an increased risk for dementia, a new study finds.

Specifically, age-related macular degeneration, cataracts and diabetes-related eye disease were linked with a higher likelihood of dementia, researchers in China said. However, one other common eye ailment, glaucoma, was not linked to dementia risk.

The new stu...

Could Cholesterol Help Drive Alzheimer's Disease?

Cholesterol made in the brain may spur development of Alzheimer's disease, a new study suggests.

Cholesterol made by cells called astrocytes is needed for controlling production of amyloid beta, a sticky protein that builds up in the brain and accumulates into the plaques that are the tell-tale sign of Alzheimer's.

Researchers say these new findings may offer insight into how and wh...

Multigenerational Study Finds Links Between ADHD, Dementia Risk

Attention-deficit/hyperactivity disorder (ADHD) appears to be somehow linked to risk of dementia and Alzheimer's disease, a new multigenerational study has found.

Parents and grandparents of people with ADHD have a higher risk of Alzheimer's and dementia than people with no ADHD in their family, Swedish researchers said.

Specifically, parents of an ADHD child have a 34% higher risk ...

Most Alzheimer's Patients Wouldn't Have Qualified for Controversial Drug's Trial: Study

U.S. approval of the Alzheimer's drug Aduhelm is already mired in controversy. Now a new study finds that most Alzheimer's patients could not have taken part in clinical trials that led to the green light.

In June, the U.S. Food and Drug Administration gave accelerated approval to Aduhelm (aducanumab) for treating patients with mild cognitive impairment or mild dementia from Alzheimer's d...

Could Traffic Noise Raise Your Odds for Dementia?

It's more than just an annoyance: Long-term exposure to traffic and train noise may increase the risk of dementia and Alzheimer's disease, Danish researchers report.

The study authors said that more than 1,200 of Denmark's nearly 8,500 cases of dementia in 2017 may have resulted from exposure to noise, which means that reducing traffic noise might help prevent the thinking, memory and beh...

Some Diabetes Meds Might Also Lower Alzheimer's Risk

Older adults who take certain diabetes drugs may see a slower decline in their memory and thinking skills, a new study suggests.

Researchers in South Korea found that among older people who'd been having memory issues, those using diabetes drugs called DDP-4 inhibitors typically showed a slower progression in those symptoms over the next few years. That was compared with both diabetes-fre...

Dirty Air, Higher Dementia Risk?

It's long been know that polluted can damage the heart and lungs, but new research finds that it's bad for your brain, too.

A long-term study by a Seattle team linked exposure to higher levels of fine particulate air pollution to an increased risk of dementia.

"We found that an increase of 1 microgram per cubic meter of exposure corresponded to a 16% greater hazard of all-cause dem...

An ALS Drug Shows Early Promise Against Alzheimer's

Could a drug used to treat amyotrophic lateral sclerosis (ALS) help people with mild Alzheimer's disease?

The results of a small new study suggest the strategy could work.

Riluzole has been used for more than 20 years to slow the progression of ALS, commonly called Lou Gehrig's disease. This phase 2 study found that the drug slowed brain metabolic decline and had a positive effect o...

Deaths From Alzheimer's Far More Common in Rural America

Death rates from Alzheimer's disease are particularly high in the rural United States, a preliminary study finds, highlighting a need for health care resources in traditionally under-served areas.

Researchers discovered that over the past two decades, rural areas in the Southeast have seen the highest death rates from Alzheimer's, at 274 per 100,000 people. That's about twice the rate as ...

Could COVID-19 Accelerate Alzheimer's Symptoms?

COVID-19 can kill you. It can rob you of your breath, cause strange blood clots, and prompt side effects that last for months after you're over the initial infection.

It's also possible that COVID-19 might impact the human brain in ways that could promote the onset of Alzheimer's disease, a new study reports.

Severely ill COVID-19 patients display biological evidence of brain injury...

Want to Avoid Dementia? Add Some Color to Your Plate

Something as simple as having a glass of orange juice in the morning or an apple at lunch could be one of the keys to protecting your brain health.

People who consumed just a half serving a day of foods high in a naturally occurring compound called flavonoids had a 20% lower risk of mental decline, according to a new study.

"We think it may have important public health i...

FDA Panel Advisor Who Panned New Alzheimer's Drug Speaks Out

An outside advisor to the U.S. Food and Drug Administration's review of the controversial Alzheimer's drug Aduhelm is now speaking out, arguing that the approval was based on dodgy science and involved questionable collaboration between regulators and the drug's maker.

"I'm not surprised at the controversy because I think it's a horrible decision. I think the FDA got it wrong," said Dr. G...

Dementia Cases Will Nearly Triple Worldwide by 2050: Study

The global total of people living with dementia will rise nearly three-fold by 2050, researchers say.

Cases are projected to increase from an estimated 57.4 million in 2019 to an estimated 152.8 million in 2050, driven mainly by population growth and aging.

This "emphasizes the vital need for research focused on the discovery of disease-modifying treatments and effective low-cost in...

'Light Flash' Treatment Might Help Slow Alzheimer's

While efforts to develop Alzheimer's medications have so far borne little fruit, new research highlights the therapeutic promise of two non-drug tools: light and sound.

According to a pair of small new studies, exposing Alzheimer's patients to an hour a day of carefully modulated light and/or sound appears, over time, to slow down the telltale brain degeneration that typifies disease prog...

Cleaning Up the Air Could Help Prevent Alzheimer's

Air pollution causes you to gasp and wheeze. Smog puts strain on your hearts and inflames your lungs.

Could dirty air also be costing you your brain health?

A trio of new studies finds that air quality appears linked to a risk of thinking declines and dementia, and bad air might even promote toxic brain proteins that are a hallmark of Alzheimer's disease.

"This is extremely ex...

Doctors Divided Over Use of Controversial New Alzheimer's Drug

The controversial new Alzheimer's drug Aduhelm is creating something of a civil war in medicine, as health networks, hospitals, insurers and individual doctors weigh impending discussions with patients about whether they should take the medication.

Many doctors believe the U.S. Food and Drug Administration "moved the goalposts" to approve Aduhelm (aducanumab) in early June, and they aren'...

Drug Shows Promise in Easing Dementia-Linked Psychosis

A drug that eases hallucinations in people with Parkinson's disease may be able to do the same for those with dementia, a new clinical trial finds.

The medication, called Nuplazid (pimavanserin), is already approved in the United States for treating hallucinations and delusions related to Parkinson's.

The new study, published July 22 in the New England Journal of Medicine, ...

1 in 20 Cases of Dementia Occurs in People Under 65

Dementia is largely a disease of old age, but a new study finds that up to 5% of all cases are among people in the prime of their lives.

Looking at 95 international studies, researchers estimated that nearly 4 million people worldwide are living with young-onset dementia -- cases that strike between the ages of 30 and 64.

In the United States, an estimated 175,000 people have the co...

Could Menopausal Hormone Therapy Reduce Women's Odds for Dementia?

Women on hormone replacement therapy (HRT) for menopause go on to have a 58% lower risk of Alzheimer's disease and other neurodegenerative conditions, a new study finds.

Although the study wasn't designed to prove cause and effect, the findings could point the way to new treatments for such diseases, according to the researchers.

"This is not the first study on the impact of hormone...

How Long Do People Want to Live?

What's better -- a long life or quality of life?

New research suggests that people balance both when thinking about their desired life span, and fears of suffering dementia or chronic pain in old age tend to limit how long they want to live.

"Dementia tops the list of conditions where people would prefer to live shorter lives -- which is a particular challenge given the rapid incr...

Two Major Health Systems Won't Administer Controversial New Alzheimer's Drug

Two major U.S. health systems say they will not administer the controversial new Alzheimer's drug Aduhelm.

The decisions by the Cleveland Clinic and Mount Sinai's Health System in New York City are the latest fallout from the U.S. Food and Drug Administration's widely criticized approval of the Biogen drug on June 7, The New York Times reported.

Many experts say there's no ...

Reading, Puzzles May Delay Alzheimer's by 5 Years: Study

An active mind in old age may delay Alzheimer's disease by up to five years, a new study suggests.

Activities like reading, writing letters, playing cards or doing puzzles may prolong brain health even for those in their 80s, researchers say.

"The key element is that you're processing information," said lead researcher Robert Wilson, a professor in the neurological sciences departme...

Medicare Mulls Coverage for Controversial Alzheimer's Drug

TUESDAY, July 13, 2021 (Healthday News) -- Medicare launched a formal process on Monday that will determine whether the agency will cover Aduhelm, the newly approved Alzheimer's drug whose high price tag and unproven benefits have prompted widespread controversy.

Medicare's announcement came the same day that leaders of two House committees that are investigating Aduhelm's approval asked ...

FDA Head Asks for Investigation Into Alzheimer's Drug Approval

MONDAY, July 12, 2021 (Healthday News) -- The U.S. Food and Drug Administration's controversial approval of the Alzheimer's drug Aduhelm should be investigated by the Office of Inspector General (OIG), FDA Acting Commissioner Dr. Janet Woodcock has said.

The FDA approved Aduhelm even though an advisory panel of outside experts said there wasn't enough proof that the drug actually works. T...

New Prescribing Instructions Tighten Use of Controversial Alzheimer's Drug

The U.S. Food and Drug Administration on Thursday issued new prescribing rules for the controversial Alzheimer's medication Aduhelm that will likely limit its use.

When first approved a month ago, the FDA said Biogen's monthly IV drug was for all Alzheimer's patients. The agency now says the drug is appropriate for patients with early or mild Alzheimer's but that it has not been studied i...

House Committees to Investigate New Alzheimer's Drug Approval

THURSDAY, July 1, 2021 (Healthday News) -- The U.S. Food and Drug Administration's controversial approval of a new Alzheimer's drug, along with its high price, is now being investigated by two House committees.

"We have serious concerns about the steep price of Biogen's new Alzheimer's drug Aduhelm and the process that led to its approval despite questions about the drug's clinical benefi...

Keeping Same Nurse for All Home Health Care May Be Crucial for Dementia Patients

Dementia patients who have the same nurse for all of their home health care visits are a third less likely to be readmitted to the hospital, a new study finds.

"While continuity of nursing care may benefit every home health care patient, it may be particularly critical for people with dementia," said study co-author Chenjuan Ma. "Having the same person delivering care can increase familia...

Healthy Living Can Lower Your Odds for Alzheimer's

Alzheimer's disease has no cure, but one expert says it may be possible to reduce the risks of developing the disease with healthy lifestyle changes.

There are two different types of Alzheimer's. Early-onset typically affects patients before age 65. Late-onset affects older adults.

"Early-onset dementia often is linked to genetics and can run in families," said Dr. Chen Zhao, a neur...

Most Cases of Dementia in U.S. Seniors Go Undiagnosed: Study

Most Americans with dementia are undiagnosed, which shows how important it is to screen and assess seniors for the disease, researchers say.

Their new analysis of data from a nationwide survey of about 6 million Americans aged 65 and older revealed that 91% of people with cognitive impairment consistent with dementia did not have a formal medical diagnosis of dementia or Alzheimer's disea...

Lilly to Seek FDA Approval for New Alzheimer's Drug

FRIDAY, June 25, 2021 (Healthday News) -- Fresh on the heels of the U.S. Food and Drug Administration's approval of the controversial Alzheimer's drug Aduhelm, the maker of a second medicine that works in similar fashion said Thursday it hopes to apply for approval of its medication later this year.

Eli Lilly said findings from a mid-stage clinical trial of 272 patients with early Alzheim...

Autopsy Study Shows How COVID Harms the Brain

The brains of people who died from COVID-19 were remarkably similar to the brains of people who die from neurodegenerative diseases such as Alzheimer's and Parkinson's, showing inflammation and disrupted circuitry, researchers report.

"The brains of patients who died from severe COVID-19 showed profound molecular markers of inflammation, even though those patients didn't have any reporte...

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